New claim added to Ireland’s no. 1 scour vaccine – Bovilis Rotavec Corona

Bovilis Rotavec Corona is now the only “one dose” neonatal vaccine with both an E. coli F5(K99) and a new F41 claim. E. coli bacteria adhere to the small intestinal epithelium by fimbriae, F5(K99) and F41 are the most commonly observed fimbriae in diarrhoeic calves1. It is therefore important to target both of these adhesins.

Bovilis® Rotavec® Corona raises antibodies to reduce the severity of diarrhoea caused by both of these offending antigens of E. coli, reduce the incidence of scours caused by rotavirus and reduce the shedding of virus by calves infected with rotavirus or coronavirus.

Bovilis® Rotavec® Corona contains bovine rotavirus inactivated Strain UK-Compton serotype G6P5, the most prevalent serotype2. Calves from vaccinated dams are also considerably less likely to shed cryptosporidium parvum3.

Vaccination can be incorporated into a control regime with halofuginone lactate during the first 7 days of life as a metaphylactic treatment against C. parvum. This two-step control programme can reduce excretion of enteropathogens and reduce the incidence of NCD4.

Bovilis® Rotavec® Corona offers flexibility and convenience as once a vial is broached for the first time it may be used once more during the next 28 days. The single shot vaccine comes in a 5, 20 and a new 50 dose presentation.


  1. Gaastra, W. and F.K. de Graaf, Host-specific fimbrial adhesins of noninvasive enterotoxigenic Escherichia coli strains. Microbiol Rev, 1982. 46(2): p. 129-61
  2. Trotz-Williams, L.A, Martin, S.W, Leslie, K.E, Duffield, T, Nydam, D.V. and Peregrine, A.S. Calf-level risk factors for neonatal diarrhea and shedding of Cryptosporidium parvum in Ontario dairy calves. Preventative Veterinary Medicine, 2007, 82:12–28
  3. Meganck, V, Hoflack, G, Piepers, S and Opsomer,G. Evaluation of a protocol to reduce the incidence of neonatal calf diarrhoea on dairy herds. Preventative Veterinary Medicine, 2015, 118(1):64-70
  4. Yan-yan, W, Cun-xi, N, Chunsheng, X et al. Effects of dietary supplementation with multispecies probiotics on intestinal epithelial development and growth performance of neonatal calves challenged with Escherichia coli K99. Journal of the Science of Food and Agriculture, 2022, 102: 4373-4383